Approach and landing phases take less than 4% of total flight time of a typical flight, but 36% of fatal aircraft accidents occur during this phase.Gust disturbances creating uncertainties during this phase are primary contributors to many unstabilized, high and fast approaches leading to catastrophic ending.This study analyses the effects of gust
Excavation near or above existing shield tunnels often results in adverse impacts HONEY COMB on tunnel stability.To ensure the serviceability of existing tunnels, this paper presents experimental and numerical studies with reference to a foundation pit case history excavated above twin-tube shield tunnels in soft soils.The experimental tests were f
Background: Subjective cognitive impairments are frequent, but poorly understood in patients with chronic fatigue.We hypothesized that maladaptive metacognitive beliefs at baseline were associated with baseline subjective cognitive impairments, that they predict subjective cognitive impairments at treatment termination, and that a reduction in mala
A series of 22 donepezil analogues were synthesized through alkylation/benzylation and compared to donepezil and its 6-O-desmethyl adduct.All the compounds were found to be potent inhibitors of both acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), two enzymes responsible for the hydrolysis of the neurotransmitter acetylcholine in Alzhe